Here are some of the most popular cartoon villains, celebrated for their iconic status and compelling villainy across various animated series and movies:

15. Jafar (Aladdin)

Jafar is a manipulative and power-hungry sorcerer who seeks to take over Agrabah, with his hypnotic staff and dark magic at his disposal.
14. Dr. Doofenshmirtz (Phineas and Ferb)

A comedic villain, Dr. Doofenshmirtz’s over-the-top evil inventions and tragic backstory make him a fan favorite.
13. Mr. Burns (The Simpsons)

The greedy, power-hungry owner of the Springfield Nuclear Power Plant is a satirical take on corporate villainy.
12. Shredder (Teenage Mutant Ninja Turtles)

Shredder is a master ninja and leader of the Foot Clan, constantly clashing with the Teenage Mutant Ninja Turtles in his quest for power.
11. Cruella de Vil (101 Dalmatians)

- A villain obsessed with fashion and dalmatian fur, Cruella’s flamboyant personality and dark motives make her unforgettable.
10. Plankton (SpongeBob SquarePants)

As the owner of the Chum Bucket, Plankton’s constant schemes to steal the Krabby Patty formula are a mix of hilarity and determination.
9. Skeletor (He-Man and the Masters of the Universe)

Known for his over-the-top schemes and menacing laugh, Skeletor is an iconic villain who remains a pop-culture favorite.
8. Azula (Avatar: The Last Airbender)

Azula, the Fire Nation princess, is a ruthless and highly skilled antagonist whose psychological depth makes her one of the most complex villains in animation.
7. Hades (Hercules)

- Voiced by James Woods, Hades is a sarcastic and witty villain who rules the Underworld. His humorous personality adds a unique charm to his malevolence.
6. Ursula (The Little Mermaid)

- Ursula, the sea witch, is a charismatic villain who tricks Ariel into giving up her voice. Her bold personality and “Poor Unfortunate Souls” song cement her as a standout Disney villain.
5. Mojo Jojo (The Powerpuff Girls)

The super-intelligent, monkey-like villain is a comedic yet dangerous adversary to the Powerpuff Girls, famous for his exaggerated speeches and schemes.
4. Maleficent (Sleeping Beauty)

Known as the “Mistress of All Evil,” Maleficent is one of Disney’s most iconic villains. Her ability to transform into a dragon adds to her terrifying legacy.
3. Lord Voldemort (Harry Potter Animated Adaptations)

In animated appearances or parodies, Voldemort maintains his status as a fearsome dark wizard bent on domination.
2. Scar (The Lion King)

Scar, voiced by Jeremy Irons, is a cunning and manipulative villain who betrays his brother Mufasa to claim the throne. His deceitful nature and iconic “Be Prepared” song make him unforgettable.
1. The Joker (Batman: The Animated Series)

Voiced by Mark Hamill, the Joker is an anarchic and sadistic villain known for his maniacal laugh and complex relationship with Batman. He is widely considered one of the best villains in any medium.
These characters resonate because of their memorable designs, compelling motivations, and the lasting impact they’ve had on audiences.